Archive for February 14th, 2008

XN and Colon cancer

Posted on February 14, 2008. Filed under: Research | Tags: , , , , , , , , , , , , , , |

1: Mol Nutr Food Res. 2005 Sep;49(9):837-43.

Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway.
Pan L, Becker H, Gerhäuser C.
Division of Toxicology and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.
Xanthohumol (XN) is one of the major prenylflavonoids found in hop cones (Humulus lupulus [...]

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XN and Diabetes

Posted on February 14, 2008. Filed under: Research | Tags: , , , , , , , , , , , , , |

1: Biochem Biophys Res Commun. 2005 Oct 28;336(3):754-61.

Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice.
Nozawa H.
R&D Laboratory, Functional Food Division, Kirin Brewery Co., Ltd., 3 Miyahara, Takasaki, Gunma 370-1295, Japan. h-nozawa@kirin.co.jp
We have examined the modulating action of xanthohumol [...]

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